Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation

Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation

Abstract Large-scale target cell isolation from patient blood preparations is one of the critical operations during drug product manufacturing for personalized cell therapy in immuno-oncology. Use of high-affinity murine antibody coated magnetic nanoparticles that remain on isolated cells is the cur...

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Bibliographic Details
Main Authors: Sabine Radisch, Mateusz P. Poltorak, Michaela Wagner, Vlad Cletiu, Christian Radisch, Irina Treise, Steffi Pann, Alexis Weigt, Sophie Artner, Stefan Dreher, Fabian Fechner, Bojana Borjan, Simon P. Fraessle, Manuel Effenberger, Eileen Benke, Gottfried Navratil, Norbert Hentschel, Dirk H. Busch, Thomas Schmidt, Christian Stemberger, Lothar Germeroth
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10320-x

Internet

https://doi.org/10.1038/s41598-022-10320-x

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