Upregulation of the APE1 and H2AX genes and miRNAs involved in DNA damage response and repair in gastric cancer

Gastric cancer remains one of the leading causes of cancer-related death worldwide, and most of the cases are associated with Helicobacter pylori infection. This bacterium promotes the production of reactive oxygen species (ROS), which cause DNA damage in gastric epithelial cells. In this study, we...

Full description

Bibliographic Details
Main Authors: Fernanda S. Manoel-Caetano, Ana Flávia T. Rossi, Gabriela Calvet de Morais, Fábio Eduardo Severino, Ana Elizabete Silva
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-06-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304219300157