Toxicity studies of drugs and chemicals in animals: An overview

Toxicity study is the investigation of either short or long-term toxic effects of a drug or chemical on animals. The toxicity is dose-dependent as asserted by Paracelsus over 500 years ago. However, short-term toxic effect is determined using median lethal dose (LD50) first introduced by Trevan in 1...

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Bibliographic Details
Main Author: S. Saganuwan
Format: Article
Language:English
Published: Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria 2017-12-01
Series:Bulgarian Journal of Veterinary Medicine
Subjects:
Online Access:http://tru.uni-sz.bg/bjvm/BJVM-December%202017%20p.%20291-318.pdf