Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

Abstract The abnormal tumor microenvironment (TME) often dictates the therapeutic response of cancer to chemo- and immuno-therapy. Aberrant expression of pericentromeric satellite repeats has been reported for epithelial cancers, including lung cancer. However, the transcription of tandemly repetiti...

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Bibliographic Details
Main Authors: Natella I. Enukashvily, Nikita V. Ponomartsev, Avanee Ketkar, Roman Suezov, Anna V. Chubar, Andrey D. Prjibelski, Daria D. Shafranskaya, Sabrina Elmshäuser, Corinna U. Keber, Vera N. Stefanova, Andrey L. Akopov, Ursula Klingmüller, Petra I. Pfefferle, Thorsten Stiewe, Matthias Lauth, Anna I. Brichkina
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05553-1

Internet

https://doi.org/10.1038/s41419-023-05553-1

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