Critical Care Cycling to Improve Lower Extremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patients

Introduction In-bed leg cycling with critically ill patients is a promising intervention aimed at minimising immobility, thus improving physical function following intensive care unit (ICU) discharge. We previously completed a pilot randomised controlled trial (RCT) which supported the feasibility o...

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Main Authors: Avelino C Verceles, Jennifer L Y Tsang, Sangeeta Mehta, Michelle E Kho, Alexander J Molloy, Margaret S Herridge, Bram Rochwerg, Ian M Ball, Joseph R Pellizzari, Jean-Eric Tarride, Diane Heels-Ansdell, John Muscedere, Francois Lamontagne, Tim Karachi, Alison Fox-Robichaud, Shane W English, Karen E A Burns, Frédérick D'Aragon, Sue Berney, Karim Serri, Erick H Duan, Lisa Buckingham, Julie Reid, Andrew J Seely, Christopher Farley, Amy M Pastva, Heather O'Grady, Laurel Kelly, Geoff Strong, Abby H Hurd
Format: Article
Language:English
Published: BMJ Publishing Group 2023-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/6/e075685.full