Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients

Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients

Pulmonary iron levels are increased in chronic obstructive pulmonary disease (COPD) patients. Iron causes oxidative stress and is a nutrient for pathogenic bacteria. Iron may therefore play an important role in the pathophysiology of COPD. The CD163-haptglobin axis plays a central role in the regula...

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Bibliographic Details
Main Authors: Andrew Higham, James M. Baker, Natalie Jackson, Rajesh Shah, Simon Lea, Dave Singh
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
iron
airway inflammation
bacteria
haemoglobin
oxidative stress
macrophages
Online Access:https://www.mdpi.com/2073-4409/11/1/2

Internet

https://www.mdpi.com/2073-4409/11/1/2

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