Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes.

Aminopeptidase N/CD13 is highly expressed by fibroblast like synoviocytes (FLS) and may play a role in rheumatoid arthritis (RA). CD13 was previously detected in human synovial fluid where it was significantly increased in RA compared to osteoarthritis. In this study we found that CD13 in biological...

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Bibliographic Details
Main Authors: Rachel L Morgan, Nilofar Behbahani-Nejad, Judith Endres, M Asif Amin, Nick J Lepore, Yuxuan Du, Andrew Urquhart, Kevin C Chung, David A Fox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5033571?pdf=render