Case Report: IL-21 and Bcl-6 Regulate the Proliferation and Secretion of Tfh and Tfr Cells in the Intestinal Germinal Center of Patients With Inflammatory Bowel Disease

Case Report: IL-21 and Bcl-6 Regulate the Proliferation and Secretion of Tfh and Tfr Cells in the Intestinal Germinal Center of Patients With Inflammatory Bowel Disease

Objective: This study aimed to investigate the effect of interleukin (IL)-21 and B cell lymphoma protein-6 on germinal center follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells and its relationship with the clinical features of inflammatory bowel disease (IBD).Methods: The expre...

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Bibliographic Details
Main Authors: Youguang Yang, Xiaodan Lv, Lingling Zhan, Lan Chen, Hui Jin, Xinping Tang, Qingqing Shi, Qiyuan Zou, Jiqiao Xiang, WeiWei Zhang, Zhaojing Zeng, Haixing Jiang, Xiaoping Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Bcl-6
follicular helper T cells
follicular regulatory T cells
germinal center
IL-21
inflammatory bowel disease
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.587445/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.587445/full

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