An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection

An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection

Hantaviruses, etiologic pathogens responsible for two severe human diseases, exist in areas ranging from Eurasia to America and remain global public health concerns. Conventionally, plaque formation assays have been used for hantavirus titering. However, hantaviruses replicate slowly within cells an...

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Bibliographic Details
Main Authors: Chuantao Ye, Dan Wang, He Liu, Hongwei Ma, Yangchao Dong, Min Yao, Yuan Wang, Hui Zhang, Liang Zhang, Linfeng Cheng, Zhikai Xu, Yingfeng Lei, Fanglin Zhang, Wei Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
viral nucleic acid synthesis inhibitors
hantavirus
FFA
T-705
BXA
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01203/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01203/full

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