The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by motoneuron death. Several cellular pathways have been described to be involved in ALS pathogenesis; however, the involvement of presynaptic stripping and the related MHC class I molecules in mutant SOD1 m...

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Bibliographic Details
Main Authors: Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti
Format: Article
Language:English
Published: PAGEPress Publications 2018-05-01
Series:European Journal of Histochemistry
Subjects:
Amyotrophic lateral sclerosis
SOD1(G93A) mice
motoneurons
synaptophysin
major histocompatibility complex I
facial axotomy.
Online Access:https://ejh.it/index.php/ejh/article/view/2904

Internet

https://ejh.it/index.php/ejh/article/view/2904

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