Screening and identification of emodin as an EBV DNase inhibitor to prevent its biological functions

Abstract Background The Epstein-Barr virus (EBV) is a prevalent oncovirus associated with a variety of human illnesses. BGLF5, an EBV DNase with alkaline nuclease (AN) activity, plays important roles in the viral life cycle and progression of human malignancies and has been suggested as a possible d...

Full description

Bibliographic Details
Main Authors: Chung-Chun Wu, Mei-Shu Chen, Ting-Ying Lee, Yu-Jhen Cheng, Hsiao-Hui Tsou, Tze-Sing Huang, Der-Yang Cho, Jen-Yang Chen
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-023-02107-x