Synthetic modified vaccinia Ankara vaccines confer cross-reactive and protective immunity against mpox virus

Abstract Background Although the mpox global health emergency caused by mpox virus (MPXV) clade IIb.1 has ended, mpox cases are still reported due to low vaccination coverage and waning immunity. COH04S1 is a clinically evaluated, multiantigen COVID-19 vaccine candidate built on a fully synthetic pl...

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Bibliographic Details
Main Authors: Flavia Chiuppesi, John A. Zaia, Miguel-Angel Gutierrez-Franco, Sandra Ortega-Francisco, Minh Ly, Mindy Kha, Taehyun Kim, Shannon Dempsey, Swagata Kar, Alba Grifoni, Alessandro Sette, Felix Wussow, Don J. Diamond
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00443-9