5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34

5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34

Abstract: A new cyclopentenone, 5-hydroxycyclopeni cillone (1), was isolated together with three known compounds, ar-turmerone (2), citreoisocoumarin (3), and 6-O-methyl-citreoisocoumarin (4), from a culture of the sponge-derived fungus Trichoderma sp. HPQJ-34. The structures of 1–4 were characteriz...

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Bibliographic Details
Main Authors: Fang Fang, Jiaying Zhao, Lijian Ding, Chunhui Huang, C. Benjamin Naman, Shan He, Bin Wu, Peng Zhu, Qijun Luo, William H. Gerwick, Xiaojun Yan, Qinwen Wang, Zaijun Zhang, Wei Cui
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Marine Drugs
Subjects:
sponge-derived fungus
cyclopentenone
Trichoderma sp. HPQJ-34
Alzheimer’s disease
Online Access:https://www.mdpi.com/1660-3397/15/8/260

Internet

https://www.mdpi.com/1660-3397/15/8/260

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