Isolation and characterization of two newly established thymoma PDXs from two relapses of the same patient: a new tool to investigate thymic malignancies

Isolation and characterization of two newly established thymoma PDXs from two relapses of the same patient: a new tool to investigate thymic malignancies

Abstract Background Thymic malignancies are a heterogeneous group of rare cancers for which systemic chemotherapy is the standard treatment in the setting of advanced, recurrent or refractory diseases. Both environmental and genetic risk factors have not been fully clarified and few target-specific...

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Main Authors: Paolo Mendogni, Roberta Affatato, Enrico Cabri, Michela Chiappa, Gloriana Ndembe, Davide Tosi, Alessandro Del Gobbo, Maddalena Fratelli, Eleonora Pardini, Iacopo Petrini, Lorenzo Rosso, Massimo Broggini, Mirko Marabese
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Thymoma
Patient-derived xenograft
Pre-clinical model
Online Access:https://doi.org/10.1186/s13046-022-02554-4

Internet

https://doi.org/10.1186/s13046-022-02554-4

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