Unbiased approach to identify and assess efficacy of human SARS-CoV-2 neutralizing antibodies

Unbiased approach to identify and assess efficacy of human SARS-CoV-2 neutralizing antibodies

Abstract Coronavirus disease 2019 (COVID-19) continues to significantly impact the global population, thus countermeasure platforms that enable rapid development of therapeutics against variants of SARS-CoV-2 are essential. We report use of a phage display human antibody library approach to rapidly...

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Bibliographic Details
Main Authors: Xia Cao, Junki Maruyama, Heyue Zhou, Yanwen Fu, Lisa Kerwin, Colin Powers, Rachel A. Sattler, John T. Manning, Alok Singh, Reyna Lim, Laura D. Healy, Sachi Johnson, Elizabeth Paz Cabral, Donghui Li, Lucy Lu, Arthur Ledesma, Daniel Lee, Susan Richards, Laura Rivero-Nava, Yan Li, Weiqun Shen, Karen Stegman, Benjamin Blair, Shinji Urata, Magumi Kishimoto-Urata, Jamie Ko, Na Du, Kyndal Morais, Kate Lawrence, Ianne Rivera, Chin-I. Pai, Damien Bresson, Mark Brunswick, Yanliang Zhang, Henry Ji, Slobodan Paessler, Robert D. Allen
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19780-7

Internet

https://doi.org/10.1038/s41598-022-19780-7

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