Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

In vitro cancer drug testing carries a low predictive value. We developed the human leiomyoma−derived matrix “Myogel” to better mimic the human tumor microenvironment (TME). We hypothesized that Myogel could provide an appropriate microenvironment for cancer cells, ther...

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Bibliographic Details
Main Authors: Katja Tuomainen, Ahmed Al-Samadi, Swapnil Potdar, Laura Turunen, Minna Turunen, Piia-Riitta Karhemo, Paula Bergman, Maija Risteli, Pirjo Åström, Riia Tiikkaja, Reidar Grenman, Krister Wennerberg, Outi Monni, Tuula Salo
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cancers
Subjects:
head and neck cancer
drug screening
human tumor microenvironment
clinical trials
in vitro 3d
Online Access:https://www.mdpi.com/2072-6694/12/1/92

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https://www.mdpi.com/2072-6694/12/1/92

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