Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing

Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing

<p>Abstract</p> <p>Background</p> <p>The beta-defensin gene cluster (DEFB) at chromosome 8p23.1 is one of the most copy number (CN) variable regions of the human genome. Whereas individual DEFB CNs have been suggested as independent genetic risk factors for several dise...

Full description

Bibliographic Details
Main Authors: Rosenstiel Philip, Hampe Jochen, Szafranski Karol, Petzold Andreas, Huse Klaus, Groth Marco, Taudien Stefan, Schreiber Stefan, Platzer Matthias
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/252

Internet

http://www.biomedcentral.com/1471-2164/11/252

Similar Items