Prediction of drug combinations by integrating molecular and pharmacological data.

Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach t...

Full description

Bibliographic Details
Main Authors: Xing-Ming Zhao, Murat Iskar, Georg Zeller, Michael Kuhn, Vera van Noort, Peer Bork
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22219721/?tool=EBI