Ser784 phosphorylation: a clinically relevant enhancer of VCP function in the DNA damage response

Ser784 phosphorylation: a clinically relevant enhancer of VCP function in the DNA damage response

Valosin-containing protein (VCP) is essential for proteostasis during many cellular processes. However, it remains uncertain how its diverse functions are selectively regulated. We recently showed that DNA damage-induced Ser784 phosphorylation specifically increases VCP function for the DNA damage r...

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Bibliographic Details
Main Author: Jieya Shao
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Molecular & Cellular Oncology
Subjects:
proteostasis
dna damage response
chemotherapy
phosphorylation
prognostic biomarker
Online Access:http://dx.doi.org/10.1080/23723556.2020.1796179

Internet

http://dx.doi.org/10.1080/23723556.2020.1796179

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