Exploring causal correlations between inflammatory cytokines and knee osteoarthritis: a two-sample Mendelian randomization

Exploring causal correlations between inflammatory cytokines and knee osteoarthritis: a two-sample Mendelian randomization

ObjectivesKnee osteoarthritis (KOA) and certain inflammatory cytokines (such as interleukin 1 [IL-1] and tumor necrosis factor alpha [TNF-a]) are related; however, the causal relationship remains unclear. Here, we aimed to assess the causal relationship between 41 inflammatory cytokines and KOA usin...

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Bibliographic Details
Main Authors: Jiayu Zhang, Kexuan Li, Xiuyue Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
knee osteoarthritis
inflammatory cytokines
Mendelian randomization
disease etiology
genetic variation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1362012/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1362012/full

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