Clinical Significance of ABCB1 in Acute Myeloid Leukemia: A Comprehensive Study

Clinical Significance of ABCB1 in Acute Myeloid Leukemia: A Comprehensive Study

ABCB1 is a member of the ATP binding cassette transporter family and high ABCB1 activity is considered as a poor prognostic factor in acute myeloid leukemia (AML) treated with intensive chemotherapy, its direct relation with drug resistance remains unclear. We evaluated ABCB1 activity in relation wi...

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Bibliographic Details
Main Authors: Thomas Boyer, Fanny Gonzales, Adeline Barthélémy, Alice Marceau-Renaut, Pauline Peyrouze, Soizic Guihard, Pascale Lepelley, Adriana Plesa, Olivier Nibourel, Carole Delattre, Marc Wetterwald, Nicolas Pottier, Isabelle Plantier, Stéphane de Botton, Hervé Dombret, Céline Berthon, Claude Preudhomme, Christophe Roumier, Meyling Cheok
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
acute myeloid leukemia
ABCB1
drug resistance
gene expression
prognosis
Online Access:https://www.mdpi.com/2072-6694/11/9/1323

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https://www.mdpi.com/2072-6694/11/9/1323

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