Parenteral immunization with a cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) adjuvanted Helicobacter pylori vaccine induces protective immunity against H. pylori infection in mice

Parenteral immunization with a cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) adjuvanted Helicobacter pylori vaccine induces protective immunity against H. pylori infection in mice

Under the trend of antibiotic resistance of H. pylori leading to the decrease of eradication rate, the development of a vaccine is the best choice to fight against H. pylori. In this study, we attempted to reduce the amounts of required antigens by using three different parenteral routes of immuniza...

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Bibliographic Details
Main Authors: Jing Chen, Youxiu Zhong, Yu Liu, Chongfa Tang, Yanbin Zhang, Bo Wei, Wangxue Chen, Meiying Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
cgamp
helicobacter pylori
parenteral immunization
post-challenge immune responses
gastric mucosa
Online Access:http://dx.doi.org/10.1080/21645515.2020.1744364

Internet

http://dx.doi.org/10.1080/21645515.2020.1744364

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