Utility of bile acids in large airway bronchial wash versus bronchoalveolar lavage as biomarkers of microaspiration in lung transplant recipients: a retrospective cohort study

Abstract Background Bronchoalveolar lavage (BAL) is a key tool in respiratory medicine for sampling the distal airways. BAL bile acids are putative biomarkers of pulmonary microaspiration, which is associated with poor outcomes after lung transplantation. Compared to BAL, large airway bronchial wash...

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Main Authors: Chen Yang Kevin Zhang, Musawir Ahmed, Ella Huszti, Liran Levy, Sarah E. Hunter, Kristen M. Boonstra, Sajad Moshkelgosha, Andrew T. Sage, Sassan Azad, Rasheed Ghany, Jonathan C. Yeung, Oscar M. Crespin, Lianne G. Singer, Shaf Keshavjee, Tereza Martinu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-022-02131-5