Multi-omics & pathway analysis identify potential roles for tumor N-acetyl aspartate accumulation in murine models of castration-resistant prostate cancer

Multi-omics & pathway analysis identify potential roles for tumor N-acetyl aspartate accumulation in murine models of castration-resistant prostate cancer

Summary: Castration-resistant prostate cancer (CRPC) is incurable and remains a significant worldwide challenge (Oakes and Papa, 2015). Matched untargeted multi-level omic datasets may reveal biological changes driving CRPC, identifying novel biomarkers and/or therapeutic targets. Untargeted RNA seq...

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Bibliographic Details
Main Authors: Mark J. Salji, Arnaud Blomme, J. Henry M. Däbritz, Peter Repiscak, Sergio Lilla, Rachana Patel, David Sumpton, Niels J.F. van den Broek, Ronan Daly, Sara Zanivan, Hing Y. Leung
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Cell biology
Proteomics
Metabolomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222003261

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222003261

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