Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardiumCentral MessagePerspective

Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardiumCentral MessagePerspective

Objective: Limited treatments exist for nonoperative chronic coronary artery disease. Previously, our laboratory has investigated extracellular vesicle (EV) therapy as a potential treatment for chronic coronary artery disease using a swine model and demonstrated improved cardiac function in swine tr...

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Bibliographic Details
Main Authors: Dwight D. Harris, MD, Sharif A. Sabe, MD, Mohamed Sabra, MD, Cynthia M. Xu, MD, Akshay Malhotra, Mark Broadwin, MD, Debolina Banerjee, MD, M. Ruhul Abid, MD, PhD, Frank W. Sellke, MD
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:JTCVS Open
Subjects:
apoptosis
extracellular vesicle
chronic coronary artery disease
chronic myocardial ischemia
hypoxia-conditioned
swine
Online Access:http://www.sciencedirect.com/science/article/pii/S2666273623001638

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http://www.sciencedirect.com/science/article/pii/S2666273623001638

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