Optimal sequencing depth design for whole genome re-sequencing in pigs

Abstract Background As whole-genome sequencing is becoming a routine technique, it is important to identify a cost-effective depth of sequencing for such studies. However, the relationship between sequencing depth and biological results from the aspects of whole-genome coverage, variant discovery po...

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Bibliographic Details
Main Authors: Yifan Jiang, Yao Jiang, Sheng Wang, Qin Zhang, Xiangdong Ding
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-3164-z