Mathematical Modeling Finds Disparate Interferon Production Rates Drive Strain-Specific Immunodynamics during Deadly Influenza Infection

The timing and magnitude of the immune response (i.e., the immunodynamics) associated with the early innate immune response to viral infection display distinct trends across influenza A virus subtypes in vivo. Evidence shows that the timing of the type-I interferon response and the overall magnitude...

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Bibliographic Details
Main Authors: Emily E. Ackerman, Jordan J. A. Weaver, Jason E. Shoemaker
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/5/906