The endoplasmic reticulum membrane protein complex subunit Emc6 is essential for rhodopsin localization and photoreceptor cell survival

The endoplasmic reticulum membrane protein complex subunit Emc6 is essential for rhodopsin localization and photoreceptor cell survival

The endoplasmic reticulum (ER) membrane protein complex (EMC) is responsible for monitoring the biogenesis and synthetic quality of membrane proteins with tail-anchored or multiple transmembrane domains. The EMC subunit EMC6 is one of the core members of EMC and forms an enclosed hydrophilic vestibu...

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Bibliographic Details
Main Authors: Kuanxiang Sun, Lu Liu, Xiaoyan Jiang, Heting Wang, Lin Wang, Yeming Yang, Wenjing Liu, Lin Zhang, Xiaohui Zhao, Xianjun Zhu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Genes and Diseases
Subjects:
ANO2
Cilium
EMC6
ER membrane protein complex
Mislocalization
Photoreceptor degeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223002076

Internet

http://www.sciencedirect.com/science/article/pii/S2352304223002076

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