Design and Characterization of Mutated Variants of the Oncotoxic Parvoviral Protein NS1
Oncotoxic proteins such as the non-structural protein 1 (NS1), a constituent of the rodent parvovirus H1 (H1-PV), offer a novel approach for treatment of tumors that are refractory to other treatments. In the present study, mutated NS1 variants were designed and tested with respect to their oncotoxi...
Main Authors: | Patrick Hauswirth, Philipp Graber, Katarzyna Buczak, Riccardo Vincenzo Mancuso, Susanne Heidi Schenk, Jürg P. F. Nüesch, Jörg Huwyler |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/15/1/209 |
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