A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines
Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin. The TBA inhibitory activity is determined by its spatial arrangement, which consist...
Main Authors: | , , |
---|---|
Format: | Article |
Sprog: | English |
Udgivet: |
MDPI AG
2021-12-01
|
Serier: | Pharmaceuticals |
Fag: | |
Online adgang: | https://www.mdpi.com/1424-8247/14/12/1326 |