A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines

Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin. The TBA inhibitory activity is determined by its spatial arrangement, which consist...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Weronika Kotkowiak, Zofia Jahnz-Wechmann, Anna Pasternak
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2021-12-01
Schriftenreihe:Pharmaceuticals
Schlagworte:
Online Zugang:https://www.mdpi.com/1424-8247/14/12/1326