Over-expression of mitochondrial antiviral signaling protein inhibits coxsackievirus B3 infection by enhancing type-I interferons production

<p>Abstract</p> <p>Background</p> <p>Recent studies have revealed that Mitochondrial Antiviral Signaling (MAVS) protein plays an essential role in the inhibition of viral infection through type I interferon (IFN) pathway. It has been shown that 3C (pro) cysteine proteas...

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Bibliographic Details
Main Authors: Zhang Qing-Meng, Song Wu-Qi, Li Yu-Jun, Qian Jun, Zhai Ai-Xia, Wu Jing, Li Ai-Mei, He Jun-Ming, Zhao Jin-Yun, Yu Xin, Wei Lan-Lan, Zhang Feng-Min
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Virology Journal
Subjects:
Online Access:http://www.virologyj.com/content/9/1/312