Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles

<p>Abstract</p> <p>Background</p> <p>Direct gene transfer into neurons has potential for developing gene therapy treatments for specific neurological conditions, and for elucidating neuronal physiology. Due to the complex cellular composition of specific brain areas, ne...

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Bibliographic Details
Main Authors: Kong Lingxin, Wang Xiaodan, Zhang Guo-rong, Cao Haiyan, Geller Alfred I
Format: Article
Language:English
Published: BMC 2008-04-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/9/37