Bioprospection and Selection of Peptides by Phage Display as Novel Epitope-Based Diagnostic Probes for Serological Detection of HTLV-1 and Use in Future Vaccines

Human T-lymphotropic virus 1 (HTLV-1) is endemic worldwide and the infection results in severe diseases, including Adult T-cell Leukemia (ATL) and HTLV-1 associated myelopathy (HAM). There are some limitations of employing the present commercial serological assays for both diagnostic and epidemiolog...

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Bibliographic Details
Main Authors: Luiz Fernando Almeida Machado, Luiz Ricardo Goulart Filho, Fabiana Almeida Araújo Santos, Leonardo Quintão Siravenha, Andrea Nazaré Monteiro Rangel Silva, Maria Alice Freitas Queiroz, Antonio Carlos Rosário Vallinoto, Marluísa Oliveira Guimarães Ishak, Ricardo Ishak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.884738/full