Bex1 is essential for ciliogenesis and harbours biomolecular condensate-forming capacity

Bex1 is essential for ciliogenesis and harbours biomolecular condensate-forming capacity

Abstract Background Primary cilia are sensory organelles crucial for organ development. The pivotal structure of the primary cilia is a microtubule that is generated via tubulin polymerization reaction that occurs in the basal body. It remains to be elucidated how molecules with distinct physicochem...

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Bibliographic Details
Main Authors: Emi Hibino, Yusuke Ichiyama, Atsushi Tsukamura, Yosuke Senju, Takao Morimune, Masahito Ohji, Yoshihiro Maruo, Masaki Nishimura, Masaki Mori
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Biology
Subjects:
Intrinsically disordered protein (IDP)
Primary cilia
Bex1
Juvenility-associated genes (JAGs)
Tubulin polymerization
Online Access:https://doi.org/10.1186/s12915-022-01246-x

Internet

https://doi.org/10.1186/s12915-022-01246-x

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