Immunophenotyping of hemocytes from infected Galleria mellonella larvae as an innovative tool for immune profiling, infection studies and drug screening

Abstract In recent years, there has been a considerable increasing interest in the use of the greater wax moth Galleria mellonella as an animal model. In vivo pharmacological tests, concerning the efficacy and the toxicity of novel compounds are typically performed in mammalian models. However, the...

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Bibliographic Details
Main Authors: Marialucia Gallorini, Beatrice Marinacci, Benedetta Pellegrini, Amelia Cataldi, Maria Luisa Dindo, Simone Carradori, Rossella Grande
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51316-z