H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6

H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6

Enrichment of basal progenitors (BPs) in the developing neocortex is a central driver of cortical enlargement. The transcription factor Pax6 is known as an essential regulator in generation of BPs. H3 lysine 9 acetylation (H3K9ac) has emerged as a crucial epigenetic mechanism that activates the gene...

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Bibliographic Details
Main Authors: Godwin Sokpor, Cemil Kerimoglu, Pauline Antonie Ulmke, Linh Pham, Hoang Duy Nguyen, Beate Brand-Saberi, Jochen F. Staiger, Andre Fischer, Huu Phuc Nguyen, Tran Tuoc
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biology
Subjects:
cortical development
neurogenesis
basal progenitors
gyrification
epigenetic regulation
H3 acetylation
Online Access:https://www.mdpi.com/2079-7737/13/2/68

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https://www.mdpi.com/2079-7737/13/2/68

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