The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration

Chen at al used fMRI to study the brain connectivity in two ageing cohorts and a mixed cohort of patients with neurodegenerative diseases. They demonstrated that with ageing the brain moves towards a more segregated modular structure, however this is disrupted by neurodegenerative diseases.

Bibliographic Details
Main Authors: Xue Chen, Joe Necus, Luis R. Peraza, Ramtin Mehraram, Yanjiang Wang, John T. O’Brien, Andrew Blamire, Marcus Kaiser, John-Paul Taylor
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02497-0