Dendritic sodium spikes are required for long-term potentiation at distal synapses on hippocampal pyramidal neurons

Dendritic integration of synaptic inputs mediates rapid neural computation as well as longer-lasting plasticity. Several channel types can mediate dendritically initiated spikes (dSpikes), which may impact information processing and storage across multiple timescales; however, the roles of different...

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Bibliographic Details
Main Authors: Yujin Kim, Ching-Lung Hsu, Mark S Cembrowski, Brett D Mensh, Nelson Spruston
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06414