Intracellular Amplifiers of Reactive Oxygen Species Affecting Mitochondria as Radiosensitizers

Intracellular Amplifiers of Reactive Oxygen Species Affecting Mitochondria as Radiosensitizers

Radiotherapy (RT) efficacy can be improved by using radiosensitizers, i.e., drugs enhancing the effect of ionizing radiation (IR). One of the side effects of RT includes damage of normal tissue in close proximity to the treated tumor. This problem can be solved by applying cancer specific radiosensi...

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Bibliographic Details
Main Authors: Hong-Gui Xu, Viktor Reshetnikov, Marit Wondrak, Lisa Eckhardt, Leoni A. Kunz-Schughart, Christina Janko, Rainer Tietze, Christoph Alexiou, Hannes Borchardt, Achim Aigner, Wenjie Gong, Michael Schmitt, Leopold Sellner, Steffen Daum, Hülya Gizem Özkan, Andriy Mokhir
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
<i>N</i>-alkylaminoferrocene
cancer
mitochondrion
reactive oxygen species
prodrug
radiotherapy
Online Access:https://www.mdpi.com/2072-6694/14/1/208

Internet

https://www.mdpi.com/2072-6694/14/1/208

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