Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors
<p>Abstract</p> <p>Background</p> <p>The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) evolved from a common ancestor. Still not completely understood is how specificity for glucocorticoids (e.g. cortisol) and mineralocorticoids (e.g. aldosterone) evo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-02-01
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| Series: | BMC Evolutionary Biology |
| Online Access: | http://www.biomedcentral.com/1471-2148/7/24 |