IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis

<p>Abstract</p> <p>Studies in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, have shown that B cells markedly influence the course of the disease, although whether their effects are protective or pathological is a matter of debate. EndoS hydro...

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Bibliographic Details
Main Authors: Benkhoucha Mahdia, Molnarfi Nicolas, Santiago-Raber Marie-Laure, Weber Martin S, Merkler Doron, Collin Mattias, Lalive Patrice H
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/209