Effect of Bcl-2 rs956572 polymorphism on age-related gray matter volume changes.

The anti-apoptotic protein B-cell CLL/lymphoma 2 (Bcl-2) gene is a major regulator of neural plasticity and cellular resilience. Recently, the Bcl-2 rs956572 single nucleotide polymorphism was proposed to be a functional allelic variant that modulates cellular vulnerability to apoptosis. Our cross-s...

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Bibliographic Details
Main Authors: Mu-En Liu, Chu-Chung Huang, Albert C Yang, Pei-Chi Tu, Heng-Liang Yeh, Chen-Jee Hong, Jin-Fan Chen, Ying-Jay Liou, Ching-Po Lin, Shih-Jen Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577673?pdf=render