Diverse Roads Taken by <sup>13</sup>C-Glucose-Derived Metabolites in Breast Cancer Cells Exposed to Limiting Glucose and Glutamine Conditions

Diverse Roads Taken by <sup>13</sup>C-Glucose-Derived Metabolites in Breast Cancer Cells Exposed to Limiting Glucose and Glutamine Conditions

In cancers, tumor cells are exposed to fluctuating nutrient microenvironments with limiting supplies of glucose and glutamine. While the metabolic program has been related to the expression of oncogenes, only fractional information is available on how variable precarious nutrient concentrations modu...

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Bibliographic Details
Main Authors: Maria Gkiouli, Philipp Biechl, Wolfgang Eisenreich, Angela M. Otto
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
nutrient deprivation
<sup>13</sup>C-metabolites
isotopologue distribution
glycolysis
Warburg effect
TCA cycle
anaplerosis
gluconeogenesis
breast cancer cells
Online Access:https://www.mdpi.com/2073-4409/8/10/1113

Internet

https://www.mdpi.com/2073-4409/8/10/1113

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