Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury

Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury

Axonal injury in the optic nerve is associated with retinal ganglion cell (RGC) degeneration and irreversible loss of vision. However, inflammatory stimulation (IS) by intravitreal injection of Pam3Cys transforms RGCs into an active regenerative state enabling these neurons to survive injury and to...

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Bibliographic Details
Main Authors: Henrike eStutzki, Christian eLeibig, Anastasia eAndreadaki, Dietmar eFischer, Günther eZeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Optic Nerve Injuries
Retinal Ganglion Cells
microelectrode array
Neuroregeneration
inflammatory stimulation
axonal imaging
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00038/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00038/full

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