O‐GlcNAcylation: cellular physiology and therapeutic target for human diseases

O‐GlcNAcylation: cellular physiology and therapeutic target for human diseases

Abstract O‐linked‐β‐N‐acetylglucosamine (O‐GlcNAcylation) is a distinctive posttranslational protein modification involving the coordinated action of O‐GlcNAc transferase and O‐GlcNAcase, primarily targeting serine or threonine residues in various proteins. This modification impacts protein function...

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Bibliographic Details
Main Authors: Lin Ye, Wei Ding, Dandan Xiao, Yi Jia, Zhonghao Zhao, Xiang Ao, Jianxun Wang
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:MedComm
Subjects:
disease
O‐GlcNAcylation
pathological processes
protein functionality
protein posttranslational modifications
therapeutic strategies
Online Access:https://doi.org/10.1002/mco2.456

Internet

https://doi.org/10.1002/mco2.456

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