Dissociation between brain amyloid deposition and metabolism in early mild cognitive impairment.

The hypothetical model of dynamic biomarkers for Alzheimer's disease (AD) describes high amyloid deposition and hypometabolism at the mild cognitive impairment (MCI) stage. However, it remains unknown whether brain amyloidosis and hypometabolism follow the same trajectories in MCI individuals....

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Bibliographic Details
Main Authors: Liyong Wu, Jared Rowley, Sara Mohades, Antoine Leuzy, Marina Tedeschi Dauar, Monica Shin, Vladimir Fonov, Jianping Jia, Serge Gauthier, Pedro Rosa-Neto, Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480449?pdf=render