YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

Summary: Benign prostatic hyperplasia (BPH) occurs when there is an imbalance between the proliferation and death of prostate cells, which is regulated tightly by estrogen signaling. However, the role of G protein-coupled estrogen receptor (GPER) in prostate cell survival remains ambiguous. In this...

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Bibliographic Details
Main Authors: Zhifu Liu, Senmao Li, Shengbin Chen, Jindong Sheng, Zheng Li, Tianjing Lv, Wei Yu, Yu Fan, Jinlong Wang, Wei Liu, Shuai Hu, Jie Jin
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Biochemistry
Molecular biology
Cell biology
Prostate disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224003468

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http://www.sciencedirect.com/science/article/pii/S2589004224003468

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