Genetics in familial hypercholesterolaemia – from genetic research to new guidelines

Genetics in familial hypercholesterolaemia – from genetic research to new guidelines

Familial Hypercholesterolaemia (FH) is genetic disorder touching up to 1 to 250 people, increasing the risk of atherosclerotic cardiovascular disease risk and early death by 3–13 times. The majority of mutations are autosomal dominant among 3 genes related to cholesterole metabolism: LDL‑receptor (L...

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Bibliographic Details
Main Authors: Edyta Kinga Prokop, Paweł Piotr Jagodziński, Stefan Grajek
Format: Article
Language:English
Published: Poznan University of Medical Sciences 2019-04-01
Series:Journal of Medical Science
Subjects:
familial hypercholesterolaemia
PCSK9 inhibitors
evolocumab
alirocumab
dyslipidaemias
Online Access:https://jms.ump.edu.pl/index.php/JMS/article/view/245

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https://jms.ump.edu.pl/index.php/JMS/article/view/245

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