Interleukin-19 impairment in active Crohn's disease patients.

The exact function of interleukin-19 (IL-19) on immune response is poorly understood. In mice, IL-19 up-regulates TNFα and IL-6 expression and its deficiency increases susceptibility to DSS-induced colitis. In humans, IL-19 favors a Th2 response and is elevated in several diseases. We here investiga...

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Main Authors: Elisabet Cantó, Esther Garcia Planella, Carlos Zamora-Atenza, Juan Camilo Nieto, Jordi Gordillo, Ma Angels Ortiz, Isidoro Metón, Elena Serrano, Esteban Vegas, Orlando García-Bosch, Cándido Juárez, Sílvia Vidal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24718601/pdf/?tool=EBI